Interestingly, the human Aac11/API5 gene, also known as AAC-11/API5L1/FIF/MIG8 and hereafter referred to as API5 (NCBI Homologene), is located at Chromosome 11p12–13 in a region frequently associated with chromosomal aberrations including amplification in glioma and breast tumor cells [34,35]. The gene discussed is API5; the disease is central nervous system cancer.