However,the immunoreactivity of progesteronereceptors in the endometrial stroma was elevated in patientswith amenorrhea on DMPA, as compared to thosewith bleeding on DMPA [23].However, among patients withbleeding on DMPA, the duration of bleeding did not correlatewith progesterone receptor quantity, indicating that additionalprocesses, namely, inflammatory or infectious, maybe contributing to the bleeding [23]. Here, PGR is linked to amenorrhea.