These authorsconcluded that although the results do not hold promise forimiquimod in therapy for chlamydial infection, the efficacy ofimiquimod may have been masked due to the obvious potentTH1 response that naturally occurs during genitaltract infection with MoPn and/or that the TLR-7 expression wasabsent or insufficient within the gastrointestinal and genitaltracts to allow a response to imiquimod. Here, TLR7 is linked to chlamydia trachomatis infectious disease.