CD44 and neoplasm: It was previously shown (Chirivi et al, 1994; Giavazzi, 1996; Orr et al, 2000; ten Kate et al, 2004) that the adhesion molecules E-Selectin, ICAM-1, and VCAM-1 on MEC and the ligands lymphocyte function-associated antigen-1, very late activation antigen-4 and CD44 on tumour cells play an important role in tumour cell adhesion to MEC and that the expression of these molecules can be induced by apoptosis (Hebert et al, 1998b; Chandra et al, 2003a).