SASH1 and neoplasm: SASH1 transcript expression was not correlated with disease recurrence, but there was a significant correlation of SASH1 expression with metastasis formation: SASH1 downregulation was correlated with the development of metachronous metastasis, defined as metastases occurring more than 6 months after resection of the primary tumour (P=0.014, Mann–Whitney U-test).