A significantly higher proportion of patients with moderate-to-severe asthma then with mild asthma had very high levels of IL-8 mRNA (above 50) and/or IL-17A mRNA values (above 50) (IL-8 mRNA: cut-off >50, p = 0.009 and IL-17A mRNA cut-off >50: p = 0.03 by Fisher's exact test respectively). This evidence concerns the gene CXCL8 and asthma.