MHC, ICAM-1, LFA-3, NCAM and CD18 were examined in MDR1-transfected breast carcinoma cell lines in this study, and no significant correlations were found for the breast carcinoma cell lines neither between LAK CML and these CAM expressions, nor between LAK CML and MHC Class I molecule expression. The gene discussed is ITGB2; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.