As shown in Figure 4a and 4b, tumours formed from T47D/NHERF-786 (72.4 ± 13.9 mg, n = 10) were significantly larger than those from T47D/Babe cells (37.7 ± 8.8 mg, n = 8) (P = 0.043), suggesting that lowered NHERF1 expression promotes tumour growth in vivo. Here, NHERF1 is linked to neoplasm.