Using a more restricted cutoff value (OD490 nm of 0.2 after subtraction of background binding in albumin-coated wells), 14 patients remained positive and these patients were later diagnosed with the following: SLE (n = 5), Sjøgren's syndrome (SS) (n = 3), discoid lupus erythematosus (n = 1), RA (n = 1), arthralgia (n = 1), urinary tract infection (n = 1), autoimmune hepatitis (n = 1), and unclassified connective tissue disease (n = 1). The gene discussed is ALB; the disease is connective tissue disorder.