Previous studies showed that the expression of Periostin is upregulated in various types of cancer, including head and neck (Gonzalez et al, 2003), colon (Bao et al, 2004, Tai et al, 2005), breast (Shao et al, 2004), lung (Sasaki et al, 2001c) and ovarian cancer (Gillan et al, 2002). Here, POSTN is linked to cancer.