Many cytokines/growth factors and their receptors, which play an important role in inflammation and endogenous response to infections, were found to be dysregulated like IL-1α (-25.9-fold; -40.3-fold), IRAK3 (-5.9; -88-fold), LTβ (+2.2-fold; +2.2-fold), Toll-like receptor 2 (-10.4-fold; -5.0-fold) and CIAS1 (-23.5-fold; -6.3-fold). The gene discussed is IRAK3; the disease is infection.