Using the reversible transgenic model to explore c-Myc driven oncogenesis in pancreatic β-cells, G. Evan has previously shown that activation of Myc on the background of suppressed apoptosis not only drives cell proliferation and expansion of β-cells, but also concomitantly induces features of advanced neoplasia such as increased invasiveness and vascularization [22]. This evidence concerns the gene MYC and neoplasm.