Recent studies have shown that IL-8 is a proangiogenic cytokine regulating tumorigenesis in DLD-1 colon cancer cells (Mizukami et al, 2005), and that it also serves as an autocrine growth factor in human colon carcinoma cells in vitro (Brew et al, 2000). Here, CXCL8 is linked to malignant colon neoplasm.