AKT1 and uterine cancer: Intracellular levels of phosphorylated (active) AKT were not modified by resveratrol at 10 μM, but we found that a dose of 100 μM of resveratrol decreased the levels of phosphorylated AKT in the three cell lines expressing constitutive levels of the kinase (KLE, RL95-2 and Ishikawa), while it had no observable effect on the other cell lines (Fig. 1C), indicating that resveratrol interferes with AKT activity in uterine cancer cells.