Other predictors of serum IgE > 56 kIU/L were a history of recurrent ear infections (OR = 0.36; p = 0.003), ethnicity (nonwhites vs. whites, OR = 2.35; p = 0.002), and number of siblings (OR for each additional sibling = 1.19; p = 0.051). The gene discussed is IGHE; the disease is ear infection.