BCL2 and cancer: Furthermore, the antiproliferative effect of Bcl-2 is separate from the antiapoptotic effect (Uhlmann et al, 1996; Huang et al, 1997), and became undetectable, whereas antiapoptotic activity persists as cancer progresses (Furth et al, 1999); however, there was no correlation between the Bcl-2 expression and prognosis in this study (Figure 2A).