Moreover, for the clinical more homogenous pN0 group (n = 25, all Patients were T1/2N0M0 and received surgery as single therapy), the median PTTG expression level of recurrent carcinomas (n = 8) was 3.82 d.u. (range: 1.90 to 5.29 d.u.)in comparison to the median level of 0.94 d.u. (range: 0.00 to 2.54 d.u.)of non-recurrent tumors (n = 17). This evidence concerns the gene PTTG1 and carcinoma.