Of the 52 tumors analyzed, 30 (58%) showed high expression of THBS3 and 22 samples (42%) showed low expression of THBS3. A comparison of the THBS3 expression levels in biopsy versus primary tumor resection or metastatic samples showed significant differences (p = 0.0001, p = 0.0001, respectively). This evidence concerns the gene THBS3 and neoplasm.