Knockout mice of steroid receptor co-activator 3 (SRC-3), a member of p160 family, exhibit infertility [22], and those of nuclear receptor interacting protein 1 (Nrip1/RIP140) are also infertile due to the blockage of the oocytes release from the Graafian follicles by the ovulatory stimuli [23]. The gene discussed is NCOA3; the disease is Infertility.