The observation of myoepithelial genes such as SFRP2, DCN, POSTN, LUM, COL1A2 and COL11A1, which showed higher expression in ER-positive compared to ER-negative breast tumours in two other breast cancer tumour profiling studies [48,49], proved the value of such an approach and demonstrated the heterogeneity of breast tumours with respect to the levels of luminal epithelial and myoepithelial gene expression. Here, COL11A1 is linked to breast neoplasm.