ESR1 and neoplasm: (Raw and annotated MPSS data are provided as Additional file 4) Expression levels of differentially upregulated transcripts in the tumour sample ranged from less than 10 tpm (ESR1, EGF, GPR150, GADD45BGIP1), to over 1,000 tpm (COL1A1, SCGB2A2, SELE, IL8).