Ninety genes belonging to the GO category of 'apoptosis', including members of the BAG family (BAG1, BAG2, BAG3), as well as members of the breast cancer 'proliferation signatures' (BUB1, PLK1, CCNE1, CCND1 and CCNB1) were also identified as up-regulated in our DTET [35,36]. The gene discussed is PLK1; the disease is breast cancer.