The Kaplan-Meier survival curves for eIF4E, VEGF, and IL-8 (Fig. 4) demonstrated that when the survival of breast cancer patients having moderate to strong expression of eIF4E is compared with the survival of patients with absent to weak expression of eIF4E through log-rank testing, there was a significantly unfavorable influence for eIF4E expression on both the overall survival (OS) (p = 0.01) and disease-free survival (DFS) (p = 0.006) of the patients (Fig. 4A,B). This evidence concerns the gene CXCL8 and breast cancer.