APOB and cardiovascular disorder: This mixed dyslipidemia (or "lipid quartet"): hypertriglyceridemia, low HDL (high-density lipoprotein)-cholesterol levels, a preponderance of small, dense LDL particles and an accumulation of cholesterol-rich remnant particles (e.g. high levels of apolipoprotein B) – emerged as the greatest "competitor" of LDL-cholesterol among lipid risk factors for cardiovascular disease.