ALB and Stroke: These non-colloid properties of albumin are increasingly recognised to be of therapeutic importance in the treatment of stroke [33] and may be of particular importance in the pathophysiology of cerebral malaria, where adherence of parasitised red blood cells to the endothelium, aggregation of red cells due to the phenomenon of rosetting, and impaired red cell deformability [34] may be influenced by the highly negative charge of the albumin molecule [26].