This analysis identified the following interesting genes from the neuroblast-specific and neuroblastoma-specific gene lists: transcription factors involved in neurogenesis TFAP2B (6p12.3; more highly expressed in neuroblasts); ASCL1 (12q23.2), SIX3 (2p21) and STAT3 (17q21.2; more highly expressed in neuroblastoma); and APOE (19q13.31) and INHBA (7p14.1; more highly expressed in neuroblastoma), which are involved in both apoptosis and neurogenesis. The gene discussed is APOE; the disease is neuroblastoma.