These reviews revealed that improvements are needed in the following areas: 1) deep vein thrombosis prophylaxis, 2) lipid profiles, 3) coordination of atrial fibrillation treatment with anticoagulation therapy, 4) dysphagia screening, 5) smoking cessation counseling, and 6) physician, EMS personnel, and public education about the urgency of stroke and the short time after a stroke that tissue plasminogen activator (tPA) treatment can be given to some patients to reverse stroke effects. This evidence concerns the gene PLAT and Stroke.