The mean absorbance value of 65 kD hsp antigen in TBM patients was [0.70 ± 0.23 (0.23–1.29)] significantly higher than the non-TBM infectious meningitis group [0.32 ± 0.14 (0.12–0.78); P < 0.001]and also higher than the non-infectious neurological disorders group [0.32 ± 0.13 (0.20–0.78); P < 0.001]. This evidence concerns the gene HSP90B2P and meningeal tuberculosis.