In contrast, FAS is overexpressed in many human tumours, including carcinoma of the breast (Milgraum et al, 1997; Wang et al, 2001b), prostate (Epstein et al, 1995; Swinnen et al, 2002), colon (Rashid et al, 1997), ovary (Gansler et al, 1997), endometrium (Pizer et al, 1998b), mesothelium (Gabrielson et al, 2001), lung (Piyathilake et al, 2000), thyroid (Vlad et al, 1999), and stomach (Kusakabe et al, 2002). Here, FAS is linked to neoplasm.