PLG and Venous thrombosis: On the other hand, in a survey of 53 Swiss family members of 23 plasminogen-deficient patients, Demarmels et al found that 5 (18%) of 28 family members with plasminogen deficiency had a history of thrombosis, whereas 5 (20%) of 25 family members with normal plasminogen levels also had a history of thrombosis.