PAX2 and CHARGE syndrome: Some characteristics of CHARGE syndrome overlap with those of other conditions including: VACTERL association, DiGeorge sequence [42], Velo-cardio-facial syndrome (VCFS), Cat Eye syndrome, retinoic acid embryopathy, and PAX2 abnormalities (The PAX2 gene is expressed in primitive cells of the kidney, ureter, eye, ear and central nervous system).