VWF and acute respiratory distress syndrome: Several biomarkers of inflammation (IL-6, IL-8, and sTNFrI/II) and epithelial (SP-D) and endothelial (vWF) injury as well as adhesion molecules (ICAM-1) have been shown to be predictors of morbidity and mortality in patients with ALI, indicating that the levels of these biomarkers are affected by the severity of the lung injury [12-14,17,18].