Notably, SET was described as part of a fusion gene with the nucleopore complex protein CAN in a patient with t(6;9)(p23;q34) acute myeloid leukaemia (AML) (Adachi et al, 1994), and it was found associated with the oncoprotein Mll (ALL1, HRX) in leukaemic cell lines (Adler et al, 1997). This evidence concerns the gene NUP214 and acute myeloid leukemia.