Notably, SET was described as part of a fusion gene with the nucleopore complex protein CAN in a patient with t(6;9)(p23;q34) acute myeloid leukaemia (AML) (Adachi et al, 1994), and it was found associated with the oncoprotein Mll (ALL1, HRX) in leukaemic cell lines (Adler et al, 1997). The gene discussed is SET; the disease is acute myeloid leukemia.