But in the subgroup of patients with severe sepsis, 185 (30.7%) of the 603 patients with severe sepsis who had been assigned to receive albumin died, and 217 (35.3%) of the 615 patients with severe sepsis who had been assigned to receive saline died (relative risk, 0.87; 95% confidence interval, 0.74–1.02; p = 0.09). Here, ALB is linked to Sepsis.