When comparing expression levels between normal colonic mucosa and lesions separately for each case group (mild/moderate dysplasia, severe dysplasia and CRC), we detected significantly higher expression levels for ERCC1 and RAI in cases with severe degree of dysplasia and for OGG1 we detected significantly higher expression levels in cases with severe degrees of dysplasia and CRC (Table 2). The gene discussed is OGG1; the disease is colorectal carcinoma.