TNF and central nervous system cancer: Additionally, CD70 overexpression was detected in a multidrug-resistant colonic cell line (SW620-MDR) (Fan et al, 2004), and as an inducible gene in TNF-alpha-stimulated human bronchial–epithelial cell line BEAS-2B (Wolf et al, 2002), and irradiated glioma cell lines (Wischhusen et al, 2002).