Five putative RGs (ESD, BTF3, HIST1H2BC, RPL30, YAP1) selected from a meta-analysis of geneChip experiments [21] were validated along with ACTB, GAPDH, RNA18S, PPIA, PGK1, RPLP0 and POLR2A by qPCR assessment of their expression levels on 18 paired normal lung and NSCLC samples. The gene discussed is POLR2A; the disease is non-small cell lung carcinoma.