Moreover, we found nostatistically significant correlation between SLE activity scoreaccording to the SLAM index and the level of tMMP-9 (ρ = 0.223;P > .05), aMMP-9 (ρ = 0.222, P > .05), and TIMP-1 (ρ = 0.111; P > .05). The gene discussed is TIMP1; the disease is systemic lupus erythematosus.