HNRNPA2B1 and systemic lupus erythematosus: Thus, the presence of hnRNP-A2 auoreactive T cells in healthy controls by itself was not surprising; a striking difference, however, was the significantly higher strength of the cellular immune response observed in SLE patients, which may be considered an indication for pathogenic involvement of these autoreactive cells and/or a lack of counter-regulation in SLE patients.