The mean fluorescence intensity (MFI) ratio of IL-10R1 was significantly higher in patients with RA than in controls (RA 2.92 ± 0.42, n = 30; controls 1.93 ± 0.16, n = 25; P < 0.05), but the MFI ratio of IL-10R2 was lower in patients with RA (RA 8.26 ± 0.59; controls 11.81 ± 0.94; P < 0.01). This evidence concerns the gene IL10RB and rheumatoid arthritis.