To determine the correlation of IL-10R1 levels and disease activity, we divided patients with RA into three groups according to disease activity using the DAS28 system – low activity (DAS28 < 3.2), moderate activity (3.2–5.1), and high activity (>5.1) – and compared the IL-10 R1 intensity of monocytes from these RA groups and controls. This evidence concerns the gene IL10RA and rheumatoid arthritis.