However, in comparison with the data from the Women's CARE Study [21], which has so far been the largest population-based case–control study of women aged 35 to 64 years, we found similar results for parity and breastfeeding, whereas the positive association between late first full-term pregnancy and ER+PR+ cancer was statistically significant in the Women's CARE Study but not in ours. The gene discussed is PGR; the disease is cancer.