Interestingly, overexpression of Cdc25, the human homolog of Mih1, is known to be closely related to cancer development [37], part of which might be related to factors in cancer development as in the case of MIH1. Positive growth factors, which can be identified by gTOW experiments, under mild bias, potentially contain factors related to cancer development such as MIH1. This evidence concerns the gene CASP4 and cancer.