On the contrary, as our results, most of previous reports regarding other cancers have shown the positive relationship between malignant potential of tumours and expression of NGF or its receptors (Geldof et al, 1998; Schneider et al, 2001; Zhu et al, 2001, 2002; Sakamoto et al, 2001a, 2001b; Kishibe et al, 2002; Davidson et al, 2003; Dolle et al, 2003). The gene discussed is NGF; the disease is cancer.