NDRG1 and neoplasm: Overexpression of NDRG1 in vitro results in morphological changes typical of cell differentiation and is inversely related to tumour growth and metastasis (Kurdistani et al, 1998; Guan et al, 2000; Bandyopadhyay et al, 2003; Bandyopadhyay et al, 2004a).