TGFA and cystic neoplasm: Although Sandgren et al. did not observe ductal elements in the pancreatic tumors from their Ela-tgfα/Ela-myc or MT-tgfα/Ela-myc double transgenic mice [53], we found that proliferating ductal lesions, multilocular cystic neoplasms and ductal adenocarcinomas occurred frequently in the pancreas of our MT-tgfα/Ela-myc mice.