TGFA and cancer: 4D and 4E), but nuclear staining was also observed in some cancer cells (arrows in fig. 1E), suggesting that TGFα might have transcriptional activity, like EGF [54]. In the adjacent "normal" or pancreatitis tissues that might have certain proliferating potential, many ductal cells, but not acinar cells, were also positive for TGFα (arrows in fig 4F).