Reports of the application of PTD in potential therapeutic development are increasing in various fields and in a variety of cell systems and include inhibition of apoptosis by transduction of anti-apoptotic Bcl-XL protein in explant cultured human chondrocytes and in human islet cells [22,23], induction of chemosensitivity by transduction of cytosine deaminase in human tumor cells [24], and inhibition of proinflammatory signaling by transduction of superreppressor IkB in Jurkat T cells [21]. The gene discussed is BCL2L1; the disease is neoplasm.