RAP1A and small cell lung carcinoma: Among the up-regulated genes were several oncogenes (epidermal growth factor receptor (ERBB) and members of the WNT (WNT5A) and RAS families (RAP1A)), growth factors (PDGFC, EGF-related, ANKRD15, RGC32, NANOS1), cyclin D2 (CCND2), a co-factor for the hypoxia inducible factor 1A (EP300), an apoptosis inhibitor (GSPT1) and an antigen (CD24) highly expressed in small cell lung carcinoma.