Six binary (sex, lung, lymph node, liver, bone, brain/CNS metastases) and eight continuous (age, time from diagnosis to metastatic disease, number of metastatic sites, ESR, C-reactive protein (CRP), haemoglobin, neutrophils, LDH) predictors were included in univariate FP analysis. The gene discussed is ESR1; the disease is metastatic neoplasm.