IGF1 and ductal breast carcinoma in situ: There was no significant association between IGF-I mRNA expression and patients' age (p = 0.3683), tumour size (p = 0.855), grade (p = 0.8789), vascular invasion (p = 0.5717), ER status (p = 0.5498) or the presence of DCIS (p = 0.8456).