CXCL10 and idiopathic pulmonary fibrosis: To demonstrate proof of the principle that CXC chemokines regulate angiogenic and angiostatic activity in IPF, Keane et al. effectively assessed the relevance of macrophage inflammatory protein [61] and CXCL10 [62] with the augmented net angiogenic activity in the in vivo model of pulmonary fibrosis.