CXCL6 and small cell lung carcinoma: We investigated the role of NF-κB (p65), a crucial transcription factor that mediates chemokine induction, in GCP-2 secretion by exposing cells to ALLN, which stabilises IκB. ALLN almost completely abolished GCP-2 secretion in H345 and H711 cells, suggesting that NF-κB is a major regulator of GCP-2 expression in SCLC.