In contrast to melanocytes, bFGF can be produced by nevus and melanoma cells and may act as an autocrine growth factor through the FGF receptors (Halaban et al, 1987; Halaban et al, 1988c; Albino et al, 1991; Scott et al, 1991; Reed et al, 1994; al-Alousi et al, 1996a, 1996b; Meier et al, 2003). This evidence concerns the gene FGF2 and melanoma.